Research Fellow in Structural Parasitology

Job title:

Analysis Fellow in Structural Parasitology

Firm

College School London

Job description

About usBiosciences is likely one of the world’s foremost centres for analysis and educating within the organic sciences and one of many largest Divisions inside UCL. The Division has a various portfolio addressing all areas of biology from protein interactions to cell operate, organism growth, genetics, inhabitants research and the surroundings. Computational modelling approaches are regularly used alongside experimental analysis programmes and far of our analysis crosses conventional boundaries, together with the connection of biodiversity to the well being of the planet. Exercise is underpinned by excessive calibre science know-how platforms and cutting-edge tools. Instructional exercise features a vary of undergraduate programmes, an increasing variety of Masters Programmes and a considerable variety of postgraduate analysis college students.Our staff, led by Dr. Josie Ferreira, is predicated within the Division of Structural and Molecular Biology. We examine how the Plasmodium parasite’s cytoskeleton is tailored for the a number of ecological niches it encounters throughout its lifecycle. This analysis requires a multidisciplinary strategy, and can present alternatives throughout structural biology, biochemistry, cell biology and biophysics.Concerning the positionWe’re looking for to nominate a Postdoctoral Analysis Fellow to affix our lab to review the bizarre cytoskeleton of the malaria parasite. Our preliminary characterisation of the parasite’s cytoskeleton (Ferreira et al. 2023 Nature Communications) revealed that Plasmodium has a outstanding vary of non-canonical microtubule constructions – some by no means noticed in different organisms.This venture will construct on this work, aiming to grasp how Plasmodium assembles and utilises its distinctive microtubule cytoskeleton to drive transmission of the parasite. It will contain utilizing cryo-EM, cryo-ET, FIB milling, and subvolume averaging to find out microtubule constructions and examine how their non-canonical types confer essential and distinctive properties to the parasite.Collaborations with native and worldwide labs may even present a variety of biophysics strategies to probe these constructions. The analysis can be carried out in a pleasant and supportive surroundings with entry to excellent amenities and within the coronary heart of London.This submit is funded by the Wellcome Belief for 3 years within the first occasion on UCL Grade 7 (£42,099 each year inclusive of London Allowance).A job description and individual specification will be accessed on the backside of this web page.When you have any queries concerning the position, please contact Dr. Josie Ferreira at josie.ferreira@ucl.ac.uk.For those who want affordable changes or a extra accessible format to use for this job on-line or have any queries concerning the software course of, please contact Biosciences staffing at biosciences.staffing@ucl.ac.uk.About youYou’ll maintain a PhD or be close to completion of a PhD in structural biology, cell biology, parasitology, biophysics or a associated self-discipline. You’ll have data and expertise with cryoEM (or electron cryo-tomography) pattern preparation, knowledge assortment and processing and/or have related data and expertise in Plasmodium (or different eukaryotic parasite) cell tradition. You’ll have demonstrated potential to handle your time and plan your individual analysis and related actions and be excited to assume creatively a few new venture.What we provideIn addition to the thrilling alternatives this position presents, we additionally supply some nice advantages a few of that are beneath:

• 41 Days vacation (27 days annual depart 8 financial institution vacation and 6 closure days)
• Extra 5 days’ annual depart buy scheme
• Outlined profit profession common revalued earnings pension scheme (CARE)
• Cycle to work scheme and season ticket mortgage
• Immigration mortgage and bills
• Relocation scheme for sure posts
• On-Website nursery
• On-site gymnasium
• Enhanced maternity, paternity and adoption pay
• Worker help programme: Workers Help Service
• Discounted medical insurance coverage

Go to https://www.ucl.ac.uk/work-at-ucl/reward-and-benefits to search out out extra.Our dedication to Equality, Range and InclusionAs London’s World College, we all know range fosters creativity and innovation, and we wish our group to signify the variety of the world’s expertise. We’re dedicated to equality of alternative, to being truthful and inclusive, and to being a spot the place all of us belong.We due to this fact notably encourage functions from candidates who’re more likely to be underrepresented in UCL’s workforce.These embody individuals from Black, Asian and ethnic minority backgrounds; disabled individuals; LGBTQI+ individuals; and for our Grade 9 and 10 roles, girls.Our division holds an Athena SWAN Silver award, in recognition of our dedication to advancing gender equality.You may learn extra about our dedication to Equality, Range and Inclusion right here: https://www.ucl.ac.uk/equality-diversity-inclusion/Obtainable paperwork

Anticipated wage

£42099 per yr

Location

North West London

Job date

Wed, 20 Mar 2024 05:09:18 GMT

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