Research Technician

Job title:

Research Technician

Company

University College London

Job description

About usUCL Institute of Ophthalmology conducts cutting-edge research, attracting principal investigators, post-doctoral fellows and MD/PhD students of the highest
international calibre to a stimulating research environment. The Institute is committed to a multi-disciplinary research portfolio that furthers an understanding of the eye and visual system linked with clinical investigations targeted to specific problems in the prevention and treatment of eye disease.
In recognition of the Institute’s international standing, the most recent Research Excellence Framework confirmed the outstanding quality of research carried out at the Institute. The combination of the Institute’s research with the expertise and resources of Moorfields Eye Hospital, which has the largest ophthalmic patient population in the Western World, facilitates advances at the forefront of vision research and provides an unparalleled setting for research, education and training in ophthalmology. We were graded #1 place in the world to study ophthalmology (CWUR 2017 world rankings). There are 4 themes at IoO:

• Development, Aging and Disease
• Rescue, Repair and Regeneration
• Visual Neuroscience and Function
• Population and Data Science

The researcher of tomorrow is critical to our goal of improving sight. We are involved in graduate training of research students (MD, MPhil, PhD), and the Institute of Ophthalmology delivers 8 highly regarded taught postgraduate programmes.The Institute employs around 250 staff, has a budget of £25m and is located next to the City of London’s main financial district near Old Street Underground station, Shoreditch High Street and a short distance from Liverpool Street Rail station.The Institute leadership is comprised of Director, Professor Andrew D. Dick, and deputy directors responsible for enabling research, education and enterprise.About the roleWe are looking to appoint a senior Research Technician at the Institute of Ophthalmology, University College London, to join the MacDonald Laboratory. This role is to support a research project entitled “Establishing killifish as a novel model of age-related and adult-onset retinal disease” led by Dr. Nicole Noel, Research Fellow. This project is funded by Moorfields Eye Charity and will be based in the Institute of Ophthalmology at the University College London. This role will support a project with Dr. Noel in the laboratory to investigate disease pathologies in a new rapidly ageing model called the turquoise killifish.The main duties of the post holder will be to provide lab managerial support for day-to-day laboratory duties, such as: killifish colony maintenance and planning, killifish husbandry, genome modification, retinal dissections for tissues collection to conduct -omics experiments, and histology. The post holder is expected to learn new techniques/skills on the job, have excellent organisational skills and will have the potential opportunity to run independent experiments.The post is graded as Grade 6 (sp 22-24; salary £35,630-£37,421 including London Allowance, depending on experience). Cost of living pay awards are negotiated nationally and are normally effective from 1st August each year. The post is funded for 18 months.About youThis post offers an exciting opportunity to join a research group led by Dr. Ryan MacDonald, focused on understanding the ageing and disease of the retina. The overarching research aim of our laboratory is to understand how a healthy eye is built and maintained throughout life. This project uses the killifish retina to approach longstanding problems in retinal neuroscience by studying age-related disease phenotypes in the rapidly ageing killifish.The MacDonald lab studies age-related disease mechanisms in the rapidly ageing killifish. Dr. Nicole Noel studies how the light-sensitive photoreceptor cells and their essential support cells, the retinal pigment epithelium, become dysfunctional and deteriorate across ageing. We use genetic engineering (cloning, transgenesis, CRISPR/Cas9 mutagenesis), multiplex cellular labelling techniques (immunofluorescence, in situ), high resolution imaging (confocal, 2-photon, spinning disk), and computational analysis to explore fundamental aspects of retinal biology.The MacDonald group consists of a diverse and including group of scientists with postdocs, PhD students and MSc students. For further information on the MacDonald lab group please see:What we offerWorking with some of the greatest intellects in the world, UCL also offers a generous pension scheme and holiday allowance, plus closure and bank holidays as well as enhanced parental pay and more. Visit to find out more.Application ProcessIf you have any queries regarding the vacancy please contact Nicole Noel ( ) and Ryan MacDonald ( )If you have any queries regarding the application process please email:A job description and person specification can be accessed at the bottom of this page.To apply for the vacancy please click on the ‘Apply Now’ button below.Please ensure you attach your CV and highest academic qualification. In addition, please ensure you provide a personal statement outlining how you meet the criteria to support your application.Our commitment to Equality, Diversity and InclusionAs London’s Global University, we know diversity fosters creativity and innovation, and we want our community to represent the diversity of the world’s talent. We are committed to equality of opportunity, to being fair and inclusive, and to being a place where we all belong.We therefore particularly encourage applications from candidates who are likely to be underrepresented in UCL’s workforce. These include people from Black, Asian and ethnic minority backgrounds; disabled people; LGBTQI+ people; and for our Grade 9 and 10 roles, women.Our department holds an Athena SWAN Silver award, in recognition of our commitment and demonstrable impact in advancing gender equality.The UCL Ways of Working supports colleagues to be successful and happy at UCL through sharing expectations around how we work – please visit to find out more.Available documents

Expected salary

£35630 – 37421 per year

Location

North West London

Job date

Thu, 06 Feb 2025 06:01:23 GMT

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