University of Edinburgh
Job title:
Research Technician
Company
University of Edinburgh
Job description
Job Description:Grade UE05: £29,179 – £33,482 per annumCMVM/Centre for Clinical Brain SciencesFull time: 35 hrs per weekFixed term: 01/06/2025 – 31/05/2027We are looking for a Research Technician that will contribute to two collaborative projects with Profs Chandran, Prof Carragher and Dr Selvaraj generating and maintaining iPSC derived monocytes/macrophages and microglia, neural and oligodendrocyte progenitor cells from iPSCs for neurodegenerative research and drug screening. The post also involves collection of peripheral blood derived monocytes (PBMCs) from patients and subsequent generation of primary macrophages from patient PBMCs. The post holder will become part of a core team within the Dementia Research Institute (DRI) at the University of Edinburgh.The Opportunity:The technician will assist with established SOPs and perform rigorous characterisation of generated cells using various molecular techniques such as DNA/RNA isolation, PCR, qPCR, fluorescence microscopy and flow cytometry. Training will be provided, as necessary. Post holder will work within 5-member stem cell technical team headed by Dr Karen Burr and guided by Post-doctoral researchers on a day-to-day basis.Your skills and attributes for success:
- B.Sc, in Biology/Biomedical Science
- Previous experience in cell culture
- Knowledge/experience of stem cells / h-iPSC
- DNA/RNA isolation
- Immunofluorescence.
ClickApplication Information:Please ensure you include the following documents in your application:
- CV
- Cover letter
As a valued member of our team you can expect:
- A competitive salary.
- An exciting, positive, creative, challenging and rewarding place to work.
- To be part of a diverse and vibrant international community.
- Comprehensive Staff Benefits, such as a generous holiday entitlement, competitive pension schemes, staff discounts, and family-friendly initiatives. Check out the full list on our
(opens in a new tab) and use our reward calculator to discover the total value of your pay and benefits.Championing equality, diversity and inclusion:The University of Edinburgh holds a Silver Athena SWAN award in recognition of our commitment to advance gender equality in higher education. We are members of the Race Equality Charter and we are also Stonewall Scotland Diversity Champions, actively promoting LGBT equality.Prior to any employment commencing with the University you will be required to evidence your right to work in the UK. Further information is available on our (opens new browser tab).The University is unable to sponsor the employment of international workers in this role. International applicants will therefore be unable to apply for and secure a Skilled Worker visa. They will only be able to take up this role if they can demonstrate an alternative right to work in the UK.Key dates to note:The closing date for applications is 28 March 2025.Unless stated otherwise the closing time for applications is 11:59pm GMT. If you are applying outside the UK the closing time on our adverts automatically adjusts to your browsers local time zone.About Us: As a world-leading research-intensive University, we are here to address tomorrow’s greatest challenges. Between now and 2030 we will do that with a values-led approach to teaching, research and innovation, and through the strength of our relationships, both locally and globally.About the Team:Centre for Clinical Brain SciencesThe Centre for Clinical Brain Sciences (CCBS; Director Professor Colin Smith), part of Edinburgh Medical School and Edinburgh Neuroscience, integrates laboratory and clinical research to study the causes, consequences and treatment of major brain disorders. Anchored in the Edinburgh BioQuarter adjacent to the Royal Infirmary of Edinburgh, and with bases at other Edinburgh hospital sites, CCBS’ locations link clinical and laboratory science with informatics and commerce to encourage the free-flowing exchange of ideas, the efficient use of clinical data and joint academic/health service delivery.CCBS comprises 64 Principal Investigators (47 staff and 17 honorary)-including 21 Personal Chairs. Of these, 70% are active NHS clinicians, which grounds the Centre’s research aims close to unmet clinical need and facilitates the translation of research findings into real-world impact. The 300+ members of CCBS conduct research of international recognition and reputation and publish approximately 300 papers a year. Major strengths include clinical trials and trial methodology, neuroimaging, neuropathology and regenerative neurology (including human stem cell research) in a wide range of conditions encompassing brain vascular disease/stroke, neurodegenerative disease, prion disease and psychiatric disorders. CCBS researchers attracted £57M in grant-funding over the last three years and collaborate widely, leading national and international clinical trials in stroke (e.g. IST-3, FOCUS, RESTART) and dementia (e.g. EPAD, AMYPAD) and playing a major role in the UK Dementia Research Institute at the University of Edinburgh. The National CJD Research and Surveillance Unit is a WHO Reference Centre for Human Prion Disease. The research generates significant and measurable impact in terms of patient health and wellbeing, NHS policy and economy, and public awareness.Within Edinburgh University’s REF 2021 submission the second largest submission was for “Neuro”; that is formally classified as Psychology, Psychiatry and Neuroscience (Unit of Assessment 4). Edinburgh was ranked second in the UK by quality (‘grade point average’, according to Research Professional) and third in the UK by the ‘power’ measure which takes into account the size of the submission as well as the quality (according to Times Higher Education; up from 4th in the last REF in 2014). The combined metric of quality and power places Edinburgh 1st in the UK. 52% of our research papers were awarded the highest score of 4*, defined as world-leading, and a further 38% were rated 3*, defined as internationally excellent. 100% of our ten impact case studies – measuring health and wealth gain- were awarded 4*, meaning they are world-leading in reach and significance. Importantly 100% of our environment was awarded 4*, meaning the context in which our research takes place is world-leading in vitality and sustainability.CCBS currently has 49 postgraduate students, mostly PhDs. It is particularly strong in clinical PhD training, with a number of innovative schemes including Rowling Scholars and Princess Margaret Research Development Fellowships. The Edinburgh Imaging Academy is a flagship for e-learning MSc and CPD courses. The Centre also has a strong record of attracting philanthropic donations to establish specialist research hubs (Anne Rowling Regenerative Neurology Clinic, Euan MacDonald Centre for MND Research, Edinburgh Dementia Prevention, MS Society Edinburgh Centre for MS Research, Muir Maxwell Epilepsy Centre, Salvesen Mindroom Research Centre, Sackler Institute for Psychobiological Research, Row Fogo Centre) that are maintained and expanded by community fundraising.For further information about our Centre is available on the ( ) (opens in a new browser tab).
Expected salary
£29179 – 33482 per year
Location
United Kingdom
Job date
Sun, 16 Mar 2025 00:16:21 GMT
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