Scientist Pre-Clinical Regulatory

Job title:

Scientist Pre-Clinical Regulatory

Company

British American Tobacco

Job description

BAT is evolving at pace into a global multi-category business. We are on a mission to decrease the health impact of our industry
To achieve our ambition, we are looking for colleagues who are ready to Be The Change. Come, join us on this journey!British American Tobacco UK has an exciting opportunity for a Scientist Pre-Clinical Regulatory in SouthamptonWhat are the key objectives and expectations from this role?Support the execution of pre-clinical capabilities, inclusive of in silico, and in vitro models, for predominantly regulatory submissions, inclusive of but not limited to FDA authorizations and approvals.The role will be accountable for supporting the tools, knowledge, and data in preclinical sciences across all BAT categories.The primary purpose for of preclinical data is to satisfy BATs duty of care by substantiating consumer product safety, meeting regulatory obligations and providing scientific substantiation of health-related claims such as reduced risk versus a cigarette.The scientific program must position BAT, and any associated acquisitions or investments, product portfolio as a trusted brand in safety assessment and must be recognized credibly externally.What is the direct impact of this role on the team or organization?The pre-clinical screening and evaluation capabilities will be applied in supporting BATs nicotine and tobacco and beyond tobacco product category strategy, in the first instance enabling launches and in the second instance identifying a driven pipeline.Role directly delivers BAT’s core purpose of A Better Tomorrow, via the science and technical framework proving the reduction in public health impact of our business.Your key responsibilities will include:

• Contribute to the delivery of internal data packages to support regulatory dossiers, such as the FDA pre-market approvals and tobacco harm reduction or modified risk claims, through the conduct of laboratory testing.
• Contribute to applying knowledge in a broad range of cell biology and in vitro toxicology methodologies, including knowledge of respiratory and / or cardiovascular diseases.
• Contribute to the delivery of high content screening approaches, data integration and analysis to support pre-clinical and consumer product safety assessments for regulatory purposes.
• Support the management of ongoing monitoring and delivery of pre-clinical studies On-Time-In-Full (OTIF) and managing project budgets.
• Input into engagement activities with key partners and prepare and deliver presentations at internal and external meetings on behalf of BAT Scientific Research
• Identify requirements and approve procedures/processes to ensure ‘Best Practice’ is followed e.g. HTA; GLP.
• Input in the development of pre-clinical assessment techniques, to deliver transformational skills and ground breaking capabilities for product assessment.
• Build an awareness of the competitor landscape and coordinate the activities of preclinical researchers, statisticians, data analysts and other research team members involved in pre-clinical studies.

What are we looking for?Experience Required

• Hands-on laboratory expertise in cell biology, molecular toxicology or pharmacology with a relevant degree and preferably PhD in biological sciences.
• Proven track record in the application of innovative in vitro approaches in the pre-clinical field to bridge to clinical endpoints and human health effects.
• Preferably, laboratory-based experience in disease pathways / mechanistic understanding / adverse outcome pathway-based approaches and genotoxicity assessment
• Demonstrable ability to apply bioinformatics tools to process and assess biological data.

Technical / Functional / Leadership Skills Required

• Project management of pre-clinical studies, preferably a collection of studies.
• Laboratory study design and data interpretation in a relevant field.
• Proven skills at scientific communication to technical and non-technical, internal, and external audiences.

Education / Qualifications / Certifications Required

• Relevant degree in biological sciences

Beneficial

• Experience of conducting science for regulatory purposes
• Experience of Good Laboratory Practice (GLP)
• PhD in biological sciences

Qualifying questions for candidates

• Do you have mammalian cell culture experience?
• Have you performed in vitro toxicology assays?

What we offer you?

• We offer a market leading annual performance bonus (subject to eligibility)
• Our range of benefits varies by country and includes diverse health plans, initiatives for work-life balance, transportation support, and a flexible holiday plan with additional incentives
• Your journey with us isn’t limited by boundaries; it’s propelled by your aspirations. Join us at BAT and become a part of an environment that thrives on internal advancement, where your career progression isn’t just a statement – it’s a reality we’re eager to build together. Seize the opportunity and own your development; your next chapter starts here.
• You’ll have access to online learning platforms and personalized growth programs to nurture your leadership skills
• We prioritise continuous improvement within a transformative environment, preparing for ongoing changes

WHY JOIN BAT?
We’re one of the few companies named as a Global Top Employer by the Top Employers Institute – certified in offering excellent employee conditions.At BAT, we champion collaboration, inclusion, and partnership as the bedrock of our values. We wish to foster an environment where every individual can thrive, irrespective of factors such as gender, sexual orientation, marital or civil partnership status, gender reassignment, race, religion or belief, colour, nationality, ethnic or national origin, disability, age, skills, experience, education, socio-economic and professional background, as well as diverse perspectives and thinking styles. We recognise that our strength lies in embracing talent from all walks of life, empowering us to develop our culture of inclusivity and better achieve our business objectives.We view career breaks not as obstacles but as opportunities and encourage everyone, without hesitation, to apply. Through our Global Returners program, we provide support to professionals seeking to re-enter the workforce after an extended absence, be it for family care, parental leave, national service, sabbatical, or starting their own venture.
Come bring your difference and see what is possible for you at BAT. Learn more about our culture and our award winning employee experience .We take pride in being a Disability Confident Employer. If you need any reasonable adjustments or accommodations to be made during the recruitment process to support you performing at your best, please inform the recruitment partner who will be in touch should your profile be selected for the role you applied for. We are wholeheartedly committed to optimising your prospects of success by making suitable arrangements so that you may showcase your full potential.

Expected salary

Location

Southampton

Job date

Wed, 19 Feb 2025 00:19:50 GMT

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