Section Manager for Microbial Products

Job title:

Section Manager for Microbial Products

Company

NHS

Job description

At NHS Blood & Transplant, we make a major contribution to medical research and development. Our Clinical Biotechnology Centre (CBC) part of Cellular and Molecular Therapeutics – supports healthcare, academic and commercial organisations through the development and manufacturing of gene & cell therapies as well as molecular (nucleic acid or protein-based) therapeutics for early-phase clinical trials and beyond. This is a chance to play a critical role as Section Manger for Microbial Products. The post involves overseeing the Microbial Manufacturing team working closely with other departments within CBC. You will have a thorough understanding of taking products from process development into GMP production with the ability to organise and manage the section workload to meet agreed schedules. Experience in plasmid DNA and working in a regulated manufacturing environment is essential.Main duties of the jobIn this role you will work under the direction of the Deputy Head of Clinical Biotechnology Centre (CBC) & Head of Manufacturing and be responsible for the day-to-day activities dealing with developments for routine Good Manufacturing Practice (GMP) grade recombinant microbially-derived product such as plasmid DNA. Your responsibilities will include: Ensuring a high standard of work and the quality of results produced. Managing staff within the Section of Microbial Products taking responsibility for day to day management including disciplinary, sickness absence and expenses. Contributing to the work of the Medicines and Healthcare products Regulatory Agency regulated laboratory services; performing, analysing, interpreting documenting and reporting routine and specialist/complex investigations and as appropriate providing advice to Sponsors/Clients/principal investigators or scientific colleagues of the clinical significance of production test results. Deputising for the Deputy & Head of Manufacturing when required, taking responsibility for a comprehensive range of CBC services, maintaining current good practice, meeting national and international professional Training scientific staff and acting as a mentor. Attending Cellular and Molecular Therapies multi-centre/national meetings and contribute to the development and implementation of new laboratory procedures and services.About usIt takes all types of people to deliver the kind of service that saves and improves lives. At NHS Blood and Transplant, youll join a team of more than 6,000 people who are making a genuine difference to communities, families, friends, relatives and more across the UK. We play a unique and special role in the NHS by helping people do something extraordinary- donate blood, blood products, organs, tissues, or stem cells to save someone in need. Our three core values are what set us apart. They guide and inspire everything we do. By being caring, expertly meeting the needs of our patients and our people, and accepting nothing less than the best quality, we can do extraordinary work and help our people to do something extraordinary in their career, too. Three small words, one big difference – Caring, Expert and Quality. Together we’ll save and improve more lives than ever. You will join us on our journey to create an inclusive workplace and aim to reflect the diverse communities we work with, and we positively encourage applications from all sectors of the community.Date posted10 February 2025Pay schemeAgenda for changeBandBand 8aSalary£53,755 to £60,504 a yearContractPermanentWorking patternFull-timeReference number005820Job locationsNHSBT500 North Bristol parkFiltonBS34 7QHJob descriptionJob responsibilitiesPlease view the attached recruitment profile which is a summary of the detailed Job Description and Person Specification for the full personal attributes we require for the role. You will need to demonstrate these throughout the recruitment process. Job descriptionJob responsibilitiesPlease view the attached recruitment profile which is a summary of the detailed Job Description and Person Specification for the full personal attributes we require for the role. You will need to demonstrate these throughout the recruitment process.Person SpecificationQualificationsEssential

• MSc or equivalent in cell and molecular therapies or a relevant biological or engineering science.
• AND
• Extensive experience in working in an R&D laboratory
• OR
• Postdoctoral experience providing specialist services for the engineering, process development, GMP tech transfer, production and testing of recombinant viral vector products.
• Demonstrates commitment to own continued professional development (CPD)

ExperienceEssential

• Extensive laboratory experience in recombinant viral vector products
• Extensive laboratory experience in advanced therapy products or biologicals
• In depth knowledge of GMP manufacturing of advanced therapy products or biologicals
• In depth understanding of relevant policies, standards and guidelines e.g. Good Manufacturing Practice, Good Laboratory Practice
• Experience in leading in validation and/or development projects
• Evidence of leading and delivering on research
• Experience of target setting and performance review
• Experience of working with Information Technology using Microsoft Office packages (Word, Excel and PowerPoint)

Person SpecificationQualificationsEssential

• MSc or equivalent in cell and molecular therapies or a relevant biological or engineering science.
• AND
• Extensive experience in working in an R&D laboratory
• OR
• Postdoctoral experience providing specialist services for the engineering, process development, GMP tech transfer, production and testing of recombinant viral vector products.
• Demonstrates commitment to own continued professional development (CPD)

ExperienceEssential

• Extensive laboratory experience in recombinant viral vector products
• Extensive laboratory experience in advanced therapy products or biologicals
• In depth knowledge of GMP manufacturing of advanced therapy products or biologicals
• In depth understanding of relevant policies, standards and guidelines e.g. Good Manufacturing Practice, Good Laboratory Practice
• Experience in leading in validation and/or development projects
• Evidence of leading and delivering on research
• Experience of target setting and performance review
• Experience of working with Information Technology using Microsoft Office packages (Word, Excel and PowerPoint)

Expected salary

£53755 – 60504 per year

Location

Filton, Gloucestershire

Job date

Wed, 12 Feb 2025 05:05:38 GMT

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