Senior Principal Scientist – Cell Pharmacology

Job title:

Senior Principal Scientist – Cell Pharmacology

Company

Job description

As our Senior Principal Scientist (SPS) Cell Pharmacology, you will be an inspirational scientist with an exceptional record of bringing your deep knowledge of quantitative cell biology and drug-target kinetics to impact on projects. You will be an experienced and passionate scientific leader, able to represent the department across a broad range of therapeutic projects and cross-site initiatives, and externally. You will contribute to, and lead, specific areas of scientific and technical innovation (including in novel modalities aligned to our strategic direction), incorporating external collaboration and partnership along with internal science builds. You will also lead drug discovery projects. Whilst this role will not manage any direct line-reports, a significant element will involve matrix leadership; you will also play a pivotal role in training and developing colleagues, including through your practical contributions from the bench.What skills will I need?We are seeking an accomplished scientific leader who can articulate a vision for our mission and set direction and inspire commitment for preclinical Discovery. The SPS should have the following skills and experience:

• PhD in Biological Science, or equivalent experience
• Significant experience and deep expertise in cell pharmacology in a drug discovery environment
• Proven track record of innovative scientific delivery through driving impactful cell pharmacology insight in drug discovery programmes, including detailed characterisation of targets and their modulation by small molecules through quantitative cell biology and drug mechanism-of-action
• Significant experience in translating drug-target kinetics through to mechanistic PKPD modelling for therapeutic dose prediction
• Proven track record of portfolio impact across a range of challenging target classes, through intellectual and laboratory-based contributions, and project leadership
• Strong external reputation in cell pharmacology and drug discovery, evidenced through wide personal network, external presentation and publication in high-impact journals, and influential roles on relevant external committees
• Significant experience in inspiring and developing a diverse world-class group, whilst working in a highly matrixed discovery project environment
• Significant experience of establishing and leading external academic and industrial collaborations, and technology change projects
• Track record of delivering results across a diverse project portfolio by driving strategic and scientific initiatives

Expected salary

Location

Cambridge

Job date

Thu, 27 Jun 2024 03:52:22 GMT

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