Senior/Principal Scientist Mass Spectrometrist

Job title:

Senior/Principal Scientist Mass Spectrometrist

Company

UCB

Job description

Make your mark for patientsWe are looking for an enthusiastic and experienced Mass Spectrometrist to join our Protein Structure and Biophysics department, located in Slough, UK.About the roleThis laboratory-based position requires expertise in the acquisition and interpretation of peptide mapping and intact protein mass spectrometry data to provide structural characterisation of our therapeutic antibody molecules.Who you’ll work withThe Mass Spectrometry team supports New Biological Entity (NBE) and New Chemical Entity (NCE) discovery from pre-portfolio investigation through to candidate selection within a department which incorporates cryo-EM, X-ray crystallography, NMR and SAXS, alongside the protein production group. This role involves working closely with the MS team, the Protein Structure & Biophysics department and several groups in UK and global discovery.What you’ll do

• Perform analysis of antibody therapeutics using mass spectrometric techniques
• Generate critical data to support candidate progression and selection
• Clearly communicate MS data on diverse antibody formats to multiple project teams
• Maintain accurate records and contribute to comprehensive data packages
• Identify and implement new technologies and methodologies
• Mentor other members of the MS team
• Ensure lab equipment is properly maintained and initiate appropriate repair and maintenance.

Interested? For this role we’re looking for the following experience and skills

• PhD and/or several years industrial laboratory-based experience in protein and peptide mass spectrometric analysis of antibodies and target proteins
• Hands-on experience and responsibility for Thermo Orbitrap / Tribrid and Waters instrumentation coupled to nanoflow and microflow UPLC systems
• Peptide mapping expertise
• Use of data analysis software packages for sequence mapping and intact mass deconvolution e.g. Protein Metrics Byos, BioPharma Finder, Proteome Discoverer or similar
• Appreciation of antibody and protein expression systems and purification protocols
• Managing or mentoring junior scientists within an MS environment
• Troubleshooting and maintenance of LC-MS systems

Are you ready to ‘go beyond’ to create value and make your mark for patients? If this sounds like you, then we would love to hear from you!About us
UCB is a global biopharmaceutical company, focusing on neurology and immunology. We are around 8,500 people in all four corners of the globe, inspired by patients and driven by science.Why work with us?
At UCB, we don’t just complete tasks, we create value. We aren’t afraid to push forward, collaborate, and innovate to make our mark for patients. We have a caring, supportive culture where everyone feels included, respected, and has equitable opportunities to do their best work. We ‘go beyond’ to create value for our patients, and always with a human focus, whether that’s on our patients, our employees, or our planet. Working for us, you will discover a place where you can grow, and have the freedom to carve your own career path to achieve your full potential.UCB and its subsidiaries encourage diversity and inclusion in the workplace; we are an Equal Opportunity Employer. We do not discriminate on the basis of race/color/religion/sex/national origin/veteran/disability/age/sexual orientation/gender identity.Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on EMEA-Reasonable_Accommodation@ucb.com. Please note should your enquiry not relate to adjustments; we will not be able to support you through this channel.

Expected salary

Location

Slough, Berkshire

Job date

Sat, 18 Jan 2025 06:30:03 GMT

To help us track our recruitment effort, please indicate in your email/cover letter where (globalvacancies.org) you saw this job posting.