Senior / Principal Scientist, Target Validation & Tractability

Job title:

Senior / Principal Scientist, Target Validation & Tractability

Company

UCB

Job description

​Faites la différence pour les patientsAbout the roleThe position is a lab-based role, requiring excellent laboratory skills, particularly on molecular and cell biology techniques. The position is a lab-based role, requiring excellent laboratory skills, particularly in cell biology/assay techniques. Additionally, we are looking for experience with creating and analysing ‘-omic’ datasets, practical experience of bioinformatic techniques and basic coding skills would be advantageous.Who you’ll work withThe successful candidate will be part of a multi-disciplinary team, focusing on the discovery and validation of novel drug targets for diseases with high unmet patient need.What you’ll do

  • Studying immunological disease pathways and biology, to generate novel insights into potential therapeutic opportunities in areas of unmet need.
  • Setting up new and running new collaborations with state-of the-art researchers on auto-immune relevant biological pathways and disease models with the aim of identifying new disease-drug target links.
  • Performing drug tractability and validation experiments, such as Gain of Function /Loss of Function assays, cell culture, flow cytometry, imaging, and other techniques. Generating and critically assessing data to support go/no-go new target decisions.
  • Contribute to the development of the technological and scientific acumen of the department, helping to enhance our target to disease translational insights, implementing novel technologies, improving workflows and robust scientific discussion
  • Present data and insights across the organization and externally
  • Work in a collaborative, matrix style right across the organisation to implement the adoption of new targets into the research portfolio.
  • Produce detailed experimental write-ups and assist in producing and collating procedures, guidelines and reports.

Interested? For this role we’re looking for the following education, experience and skills

  • Educated to degree level with industry experience, PhD desirable.
  • Experience in a range of cellular and molecular biology techniques – for example: cell culture, flow cytometry, high content imaging, ELISA or MSD, Western blotting, qPCR, cloning, transfection/siRNA/CRISPR gene-editing.
  • Experience with bioinformatic tools for analysing large NGS/’omic’ datasets and basic coding skills
  • Good communication skills and comfortable presenting experimental data at cross-functional meetings.
  • Knowledge of coding is advantageous.
  • Experience with use of bioinformatic tools to visualise and curate from large datasets.
  • Ability to work within a team in a fast-paced environment with changing priorities.
  • Highly motivated and driven to exceed goals.

Êtes-vous prêt à « aller au-delà » pour créer de la valeur et faire la différence pour les patients ? Si cela vous parle, alors nous aimerions vous connaitre !À propos de nousUCB est une société biopharmaceutique mondiale, spécialisée dans la neurologie et l’immunologie. Nous sommes environ 8 500 personnes aux quatre coins du monde, inspirées par les patients et motivées par la science.Pourquoi travailler pour nous ?Chez UCB, nous ne nous limitons pas à réaliser des tâches, nous créons de la valeur. Nous ne craignons pas d’aller de l’avant, de collaborer et d’innover pour faire la différence auprès des patients. Nous avons une culture de bienveillance et solidarité où chacun se sent inclus, respecté et a des chances équitables de faire de son mieux. Nous « allons au-delà » pour créer de la valeur pour nos patients, et toujours dans une optique humaine, que ce soit pour nos patients, nos employés ou notre planète. En travaillant pour nous, vous découvrirez un monde où vous pourrez grandir et aurez la liberté de tracer votre propre chemin de carrière et accomplir votre plein potentiel.En savoir plus sur la durabilité chez UCB et comment elle est intégrée dans notre approche commercialeUCB et ses filiales encouragent la diversité et l’inclusion au travail; Nous sommes un employeur équitable. Nous ne discriminons pas sur la base de la race/la couleur/la religion/le sexe/l’origine nationale/l’ancien combattant/le handicap/l’âge/l’orientation sexuelle/l’identité de genre.Si vous avez besoin d’adaptation à notre processus afin de mettre en valeur vos compétences, veuillez nous contacter à l’adresse EMEA-Reasonable_Accommodation@ucb.com. À noter que si votre message ne concerne pas une demande d’ajustements, nous ne pourrons pas vous assister par ce biais.

Expected salary

Location

Slough, Berkshire

Job date

Thu, 18 Jul 2024 06:33:44 GMT

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