Senior Research Associate (Bacterial DNA Replication)
Newcastle University
Starting salary: £46,485 per annumNewcastle University is a great place to work, with excellent . We have a generous holiday package; plus the opportunity to buy more, great pension schemes and a number of health and wellbeing initiatives to support you.Closing Date: 06 November 2024The RoleA Senior Research Associate is required to support laboratory of Professor Heath Murray, focusing on understanding the mechanism of DNA replication initiation in bacteria ( ). This Wellcome Trust funded position is based at the Centre for Bacterial Cell Biology (CBCB) within the Biosciences Institute at Newcastle University.Bacteria are the most abundant species on Earth, playing central roles in human health and in the environment. A molecular understanding of bacterial cell cycle activities is necessary to control their growth and proliferation. Despite years of study, fundamental aspects of DNA replication initiation in bacteria remain poorly understood. Specifically, the architecture of nucleoprotein complexes required to load helicase(s), and the temporal set of activities that replication initiation proteins perform during the helicase loading reactions, are unclear.This post will involve laboratory-based research, mainly focused on purification of DNA replication proteins and reconstitution of their activities in vitro. This project will combine genetics, biochemistry, and cryo-electron microscopy to unravel the molecular mechanisms of bacterial helicase loading, to near-atomic resolution, at both a chromosome origin and a repaired replication fork.This is a full-time fixed term post to 31/12/2030.For informal enquiries please contact: Professor Heath MurrayAs part of our commitment to career development for research colleagues, the University has developed 3 levels of . These profiles set out firstly the generic competences and responsibilities expected of role holders at each level and secondly the general qualifications and experiences needed for entry at a particular level.Please note that if you are successful to this role, you will require medical clearance before you can commence in the role.Key Accountabilities
The PersonKnowledge, Skills and Experience
Attributes and Behaviour
Qualifications
Newcastle University is a global University where everyone is treated with dignity and respect. As a University of Sanctuary, we aim to provide a welcoming place of safety for all, offering opportunities to people fleeing violence and persecution.We are committed to being a fully inclusive university which actively recruits, supports and retains colleagues from all sectors of society. We value diversity as well as celebrate, support and thrive on the contributions of all of our employees and the communities they represent. We are proud to be an equal opportunities employer and encourage applications from individuals who can complement our existing teams, we believe that success is built on having teams whose backgrounds and experiences reflect the diversity of our university and student population.At Newcastle University we hold a silver award in recognition of our good employment practices for the advancement of gender equality. We also hold a Bronze award in recognition of our work towards tackling race inequality in higher education REC. We are a employer and will offer an interview to disabled applicants who meet the essential criteria for the role as part of the offer and interview scheme.In addition, we are a member of the Euraxess initiative supporting researchers in Europe.Requisition ID: 27718
£46485 per year
Newcastle
Thu, 31 Oct 2024 23:52:22 GMT
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