Senior Scientist Bioscience COPD/IPF

Job title:

Senior Scientist Bioscience COPD/IPF

Company

AstraZeneca

Job description

Position: Senior Scientist Bioscience COPD/IPFLocation: Cambridge, UKCompetitive Salary & Excellent Company BenefitsWe are currently looking for highly motivated scientists with excellent laboratory skills to join the Bioscience COPD/IPF team within the Early Respiratory & Immunology Department, based in Cambridge, UK. You will collaborate with scientists from a variety of functional teams in Cambridge and with our sites in Gothenburg, Sweden and Gaithersburg, US.Main Duties and ResponsibilitiesAs part of the team you will develop, design, complete and analyse in vitro experiments to progress our drug discovery projects and publishable scientific insights in chronic lung diseases such as COPD and IPF. You are encouraged to stay up to date with emerging literature and take a part in scientific discussion to add input in experimental design and data interpretation to drive projects and techniques within the team. Teamwork is critical for successful project delivery, and you will proactively contribute to a vibrant and innovative working environment.This is a laboratory-based position where you will be involved in multiple ongoing projects, utilising primary cells, cell lines and ex vivo models. We are looking for someone with strong experience in culturing and use of human primary cells, immunoassays, protein and RNA analysis and immunohistochemistry.Accountabilities:

• An effective team member, supporting drug discovery projects to meet their objectives
• Can conduct, where appropriate, more than one area of work in parallel and to agreed timelines
• Can interpret experimental data and play a meaningful role in the planning of further experiments
• Contribution to writing peer-reviewed publications, abstracts and patents
• Responsible for ensuring that their scientific knowledge influences project progression in accordance with portfolio priorities
• Ensures that work is performed in alignment with appropriate Safety, Health & Environment (SHE), quality and compliance standards

Essential Requirements

• A PhD or BSc/MSc with relevant experimental experience
• Candidates should be able to work independently, take own initiatives and have a positive, results oriented and problem-solving attitude.
• Highly organized and self-motivated, collaborator
• Excellent English oral and written communication skills
• Good knowledge and understanding of chronic respiratory diseases such as COPD or IPF (and ideally experience researching these diseases)
• Strong hands-on experience with human primary cell culture and primary cell assays
• Experience in the use of immunological, pharmacological, cellular or molecular methods (in vitro, ex vivo) relevant to the study of respiratory disease (for example, ELISA, immunofluorescence, immunohistochemistry, flow cytometry, western blotting, molecular biology, gene editing, imaging and image analysis)

Desirable Skills & Experience

• Experience working with human lung epithelial cells, fibroblasts, precision cut lung slices or human lung explants
• Knowledge or experience of the drug discovery process

Interested? We can’t wait to hear from you.Please apply by submitting your CV by COB 11th November 2024.Date Posted 28-Oct-2024Closing Date 11-Nov-2024Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.

Expected salary

Location

Cambridge

Job date

Wed, 30 Oct 2024 07:58:47 GMT

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