Senior Scientist – Mass Spectrometry

Job title:

Senior Scientist – Mass Spectrometry

Company

GlaxoSmithKline

Job description

Part of R&D, Large Molecule Discovery is accountable for the discovery of antibodies and other protein-based therapeutics. We work across different therapeutic areas from oncology to autoimmunity and infectious diseases, harnessing cutting edge design and engineering technology. Within Large Molecule Discovery, the Developability team assesses our lead molecules using a range of biophysical methods to determine their physical characteristics and stability.We are looking to hire a mass-spectrometrist to characterise our molecules in depth. The work will be focussed on peptide mapping to identify and quantify post-translational modifications, top-down methods to characterise complex modalities such as bispecific antibodies, and the development of new methods, as per pipeline need and candidate expertise. We have a state-of-the-art suite of high-resolution mass spectrometers at Stevenage, including a Bruker TimsToF and EMR/UHMR Orbitrap instruments.This role is ideally suited to a recent PhD graduate or a scientist with lab experience looking to take the next step in their career.We create a place where people can grow, be their best, be safe, and feel welcome, valued and included. We offer a competitive salary, an annual bonus based on company performance, healthcare and wellbeing programmes, pension plan membership, and shares and savings programme.We embrace modern work practises; our Performance with Choice programme offers a hybrid working model, empowering you to find the optimal balance between remote and in-office work.Discover more about our company wide benefits and life at GSK on our webpageIn this role you will

• Plan, design, and execute experiments to characterise proteins using mass spectrometry, both top-down and bottom-up
• Communicate experimental outcomes to non-experts on multi-disciplinary project teams
• Develop new mass spec methods to characterise novel therapeutic modalities and formats
• Keep high quality electronic lab notebooks and write scientific reports

Why you?Basic Qualifications & Skills:We are looking for professionals with these required skills to achieve our goals:

• PhD or equivalent experience in chemical or biological sciences.
• Demonstrated, hands-on experience characterising proteins or peptides by mass-spectrometry

Preferred Qualifications & Skills:Please note the following skills are not necessary, just preferred, if you do not have them, please still apply:

• Experience in troubleshooting MS instruments/methods
• Familiarity with antibody drug discovery processes
• Experience characterising proteins using biophysical and biochemical methods

Closing Date for Applications – 24th April 2024 (COB)Please take a copy of the Job Description, as this will not be available post closure of the advert.When applying for this role, please use the ‘cover letter’ of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people over the next 10 years. R&D is committed to discovering and delivering transformational vaccines and medicines to prevent and change the course of disease. Science and technology are coming together in a way they never have before, and we have strong tech-enabled capabilities that allow us to build a deeper understanding of the patient, human biology and disease mechanisms, and transform medical discovery. We are revolutionising the way we do R&D. We’re uniting science, technology and talent to get ahead of disease together.Find out more:.Why Us?GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organization where people can thrive. Getting ahead means preventing disease as well as treating it, and we aim to positively impact the health of 2.5 billion people by the end of 2030.Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a workplace where everyone can feel a sense of belonging and thrive as set out in our Equal and Inclusive Treatment of Employees policy. We’re committed to being more proactive at all levels so that our workforce reflects the communities we work and hire in, and our GSK leadership reflects our GSK workforce.As an Equal Opportunity Employer, we are open to all talent. In the US, we also adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to neurodiversity, race/ethnicity, colour, national origin, religion, gender, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class*(*US only).We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on or 0808 234 4391.Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a UK Recruitment FAQ guide. Click the and scroll to the Careers Section where you will find answers to multiple questions we receiveAs you apply, we will ask you to share some personal information which is entirely voluntary. We want to have an opportunity to consider a diverse pool of qualified candidates and this information will assist us in meeting that objective and in understanding how well we are doing against our inclusion and diversity ambitions. We would really appreciate it if you could take a few moments to complete it. Rest assured, Hiring Managers do not have access to this information and we will treat your information confidentially.Important notice to Employment businesses/ AgenciesGSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK’s commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit GSK’s Transparency Reporting site.

Expected salary

Location

Stevenage, Hertfordshire

Job date

Thu, 11 Apr 2024 23:37:07 GMT

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