Senior Scientist, Medicinal Chemistry

Job title:

Senior Scientist, Medicinal Chemistry

Firm

GlaxoSmithKline

Job description

The Modality Platform Applied sciences group specialises within the design and improvement of novel approaches for the synthesis of a spread of molecular courses together with oligonucleotides, focused protein degraders and antibody drug conjugates to speed up drug discovery. The group brings collectively medicinal chemistry, artificial natural chemistry and automation abilities and expertise to ship business main platforms, uniting science, know-how, and expertise to get forward of illness collectively.We create a spot the place individuals can develop, be their finest, be protected, and really feel welcome, valued, and included. We provide a aggressive wage, an annual bonus primarily based on firm efficiency, healthcare and wellbeing programmes, pension plan membership, and shares and financial savings programme.Uncover extra about our firm huge advantages and life at GSK on our webpageOn this function you’ll

• Perform experimental work inside the Modality Platform Applied sciences group. This can contain designing and executing artificial plans to ship small portions of compound for organic analysis. Along with the laboratory part of this function, this will even contain analysing knowledge, and designing compounds to check medicinal chemistry hypotheses. In distinction to utilizing artificial natural chemistry to find new reactions or methodology, this function will contain making use of synthesis to find compounds with improved organic exercise.
• Develop and implement methods for environment friendly and high-quality synthesis, purification, and characterization of difficult molecular scaffolds.
• Collaborate with cross-functional groups to use our revolutionary modalities platforms to the invention of latest therapeutics.
• Keep updated with the most recent developments in chemistry and applied sciences aligned to the group remit and consider their potential purposes within the discovery of therapeutics.

Why you?Fundamental {Qualifications} & Expertise:We’re searching for professionals with these required abilities to attain our targets:

• Excellent diploma or equal in chemistry and a PhD/DPhil (or about to be awarded a PhD) in medicinal chemistry/artificial chemistry/chemical biology.
• Good monitor data working within the lab
• A sound understanding of sensible natural chemistry and present artificial methodology is a necessary requirement as proven by an intensive monitor document of excessive artificial productiveness, route design and downside fixing. Proof of making use of revolutionary artificial chemistry to resolve issues is required.
• Skill to know, interpret and talk advanced scientific knowledge.
• Wonderful written and oral communication abilities enabling environment friendly presentation of scientific findings to each technical and non-technical audiences.
• Monitor document of peer reviewed publications. A document of presenting at scientific conferences can also be anticipated.

Most well-liked {Qualifications} & Expertise:Please observe the next abilities usually are not needed, simply most well-liked, when you would not have them, please nonetheless apply:

• An consciousness and understanding of medicinal chemistry ideas and their use inside a drug discovery setting
• Design, implement and downside resolve as applicable, with minimal supervision
• Information of therapeutic purposes of oligonucleotides, antibody drug conjugates, focused protein degraders and the drug improvement course of
• Consideration to element and talent to work in a fast-paced and dynamic setting

Closing Date for Purposes – 18 April 2024 (COB)Please take a replica of the Job Description, as this is not going to be accessible submit closure of the advert.
When making use of for this function, please use the ‘cowl letter’ of the net utility or your CV to explain the way you meet the competencies for this function, as outlined within the job necessities above. The knowledge that you’ve got offered in your cowl letter and CV might be used to evaluate your utility.At GSK, we have now daring ambitions for sufferers, aiming to positively impression the well being of two.5 billion individuals over the subsequent 10 years. R&D is dedicated to discovering and delivering transformational vaccines and medicines to stop and alter the course of illness. Science and know-how are coming collectively in a approach they by no means have earlier than, and we have now sturdy tech-enabled capabilities that permit us to construct a deeper understanding of the affected person, human biology and illness mechanisms, and remodel medical discovery. We’re revolutionising the best way we do R&D. We’re uniting science, know-how and expertise to get forward of illness collectively.Discover out extra:.Why Us?GSK is a worldwide biopharma firm with a particular goal – to unite science, know-how and expertise to get forward of illness collectively – so we will positively impression the well being of billions of individuals and ship stronger, extra sustainable shareholder returns – as a company the place individuals can thrive. Getting forward means stopping illness in addition to treating it, and we purpose to positively impression the well being of two.5 billion individuals by the top of 2030.Our success completely will depend on our individuals. Whereas getting forward of illness collectively is about our ambition for sufferers and shareholders, it’s additionally about making GSK a spot the place individuals can thrive. We wish GSK to be a office the place everybody can really feel a way of belonging and thrive as set out in our Equal and Inclusive Remedy of Workers coverage. We’re dedicated to being extra proactive in any respect ranges in order that our workforce displays the communities we work and rent in, and our GSK management displays our GSK workforce.As an Equal Alternative Employer, we’re open to all expertise. Within the US, we additionally adhere to Affirmative Motion ideas. This ensures that each one certified candidates will obtain equal consideration for employment with out regard to neurodiversity, race/ethnicity, color, nationwide origin, faith, gender, being pregnant, marital standing, sexual orientation, gender id/expression, age, incapacity, genetic data, navy service, lined/protected veteran standing or some other federal, state or native protected class*(*US solely).We consider in an agile working tradition for all our roles. If flexibility is vital to you, we encourage you to discover with our hiring group what the alternatives are.Do you have to require any changes to our course of to help you in demonstrating your strengths and capabilities contact us on or 0808 234 4391.Please observe ought to your enquiry not relate to changes, we won’t be able to assist you thru these channels. Nevertheless, we have now created a UK Recruitment FAQ information. Click on the and scroll to the Careers Part the place you’ll discover solutions to a number of questions we obtainAs you apply, we’ll ask you to share some private data which is fully voluntary. We wish to have a chance to think about a various pool of certified candidates and this data will help us in assembly that goal and in understanding how properly we’re doing in opposition to our inclusion and variety ambitions. We might actually respect it when you might take just a few moments to finish it. 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GSK shall due to this fact not be answerable for any charges arising from such actions or any charges arising from any referrals by employment companies/companies in respect of the vacancies posted on this web site.Please observe that in case you are a US Licensed Healthcare Skilled or Healthcare Skilled as outlined by the legal guidelines of the state issuing your license, GSK could also be required to seize and report bills GSK incurs, in your behalf, within the occasion you’re afforded an interview for employment. This seize of relevant transfers of worth is critical to make sure GSK’s compliance to all federal and state US Transparency necessities. For extra data, please go to GSK’s Transparency Reporting web site.

Anticipated wage

Location

Stevenage, Hertfordshire

Job date

Thu, 04 Apr 2024 05:58:46 GMT

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