Senior Technician – Research (Fixed term)

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Biosciences, Microbiology, Brewing & Biotechnology
Location:  Sutton Bonington
Wage: 
£27,584 to £31,875
every year (pro-rata if relevant) relying on abilities and expertise.
Closing Date:  Monday 22 January 2024
Reference:  SCI618723

Do you wish to contribute in the direction of the event of lateral stream check for Chagas illness? 

Chagas illness is brought on by the parasite Trypanosoma cruzi and it is without doubt one of the main uncared for tropical ailments, affecting 6 million individuals worldwide, primarily undiagnosed, with 75 million estimated to be in danger.

Chagas is endemic in Central and South America however spreading quick on account of international warming and international migration, inflicting extreme cardiac complication, usually deadly, many years after the primary an infection.

We computationally engineered variants of a key antigen and examined them in opposition to human sera samples from Chagas sufferers. We at the moment are prepared to supply the primary LFT prototype (patent pending) to check long-term stability. 

Your position will probably be to precise and purify the engineered variants in E. coli in giant scale following a standardised course of. Expertise in utilizing middle-size fermenters and/or biophysical strategies could be advantageous. 

The challenge is sponsored by MRC, initially to thirty first December 2024, however might be prolonged additional primarily based on future grant functions. The challenge is in collaboration with the LSHTM and non-for-profit organisation TroZonX17.

Minimal qualification required is an MSc in Biochemistry, Structural Biology, or associated disciplines OR Equal {qualifications} plus appreciable work expertise in related position OR Substantial work expertise in related position.

A PhD plus related technical/scientific expertise targeted on protein expression and purification aimed to structural and/or biophysical research could be a bonus.

The work will probably be primarily based on the College of Nottingham within the Faculty of Biosciences on the Sutton Bonington Campus.

This position is obtainable on a hard and fast time period foundation till 31/12/2024. Hours of labor are full time (36.25 hours). Job share preparations could also be thought of.

For casual enquiries, please contact Dr Ivan Campeotto at: [email protected]

Please word that functions despatched on to this electronic mail handle won’t be thought of.

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