Technical Specialist

Job title:

Technical Specialist

Firm

Newcastle College

Job description

Wage: £29,605 to £30,487 with development to £32,982 every yearNewcastle College is a superb place to work, with glorious . We’ve a beneficiant vacation bundle; plus the chance to purchase extra, nice pension schemes and various well being and wellbeing initiatives to assist you.Closing Date: 30 April 2024The PositionYou may be a part of a multidisciplinary crew that features biologists, structural biologists and chemists based mostly within the Newcastle Most cancers Centre that goals to determine new therapeutic approaches to deal with most cancers. You will discover out extra about our analysis on our devoted internet pages:You’ll report back to Professor Jane Endicott, Professor Martin Noble and the Institute Technical Supervisor. As laboratory co-ordinator you’ll preserve oversight of this system’s laboratory exercise. You’ll present specialised technical assist for protein expression, purification, characterisation, crystallisation and construction willpower to a gaggle utilizing structural and chemical biology to know the roles and mechanisms of cyclin-dependent protein kinases to generate hypotheses for drug discovery.You’ll help within the operating of the insect cell laboratory. An in-depth information of technical or scientific practices, strategies and procedures gained by expertise and/or formal qualification will allow you to supply a spread of technical assist actions.You should be dependable, versatile and capable of work effectively, each unsupervised and in an interdisciplinary crew. Working as a part of an expert neighborhood you’ll present a technical assist service to employees and college students by primarily following established working patterns, resolving most challenges regardless of extra senior colleagues.Primarily based within the School of Medical Sciences you’ll be part of the Most cancers Analysis Horizons Therapeutic Innovation Newcastle Drug Discovery Group.The place is funded by the Medical Analysis Council and is on the market on a hard and fast time period foundation till 30/09/2026.Casual approaches might be made to Professor Jane Endicott ( ) or Professor Martin Noble ( ).Details about the School of Medical Sciences is on the market at: .Key Accountabilities

• You may be the laboratory co-ordinator for the group. Sustaining oversight of laboratory exercise and aiding with the graceful operating of the group
• You may be chargeable for growing new protocols, underneath tutorial course and following unbiased literature evaluation
• You’ll commonly seek the advice of with tutorial employees relating to growing new or improved strategies for experimental programs
• You’ll troubleshoot technical points with tools and methodology as wanted in session with others within the analysis group
• Help within the operating of the insect cell laboratory
• Contribute to the structural biology programme and to be accountable, following session with tutorial employees, for (i) recombinant expression of proteins in insect and bacterial cells; (ii) protein characterisation and assay improvement; (iii) protein crystallisation
• Monitoring the passable operation of laboratory biophysics tools housed throughout the group (particularly the fluorescent plate reader (PHERAstar, BMG Labtech) and FPLCs for protein purification and characterisation (Cytiva) and preserve tools by scheduling and aiding of their common cleansing and calibration
• Current outcomes at inside and exterior conferences and help with writing publications
• Maintain glorious laboratory data of all experimental procedures and outcomes, enabling interpretation with crew members situated at totally different institutes
• It’s best to have the ability to talk successfully, orally and in writing, to share info with colleagues
• It is possible for you to to contribute to laboratory conferences e.g. drawback fixing, inside seminars, journal membership
• Help with the completion and updating of a variety of security paperwork, e.g., threat assessments and security laboratory data (e.g. COSHH) in session with tutorial employees
• You’ll full accident reporting and help with investigations
• Preserve in-depth and up-to-date well being and security information related to the specialism
• Organise and help generally laboratory duties akin to shops, tools upkeep and basic cleansing
• Supply and negotiate with suppliers for a spread of things together with specialist elements/tools
• Liaise commonly with the road supervisor to prioritise duties and organise workload for the passable completion of inter-institute analysis actions, requiring entry to a number of services and tools
• Liaise with bioscience and chemistry colleagues to determine and optimise alternatives for additional collaboration
• Present recommendation, help and coaching to tutorial, technical and analysis employees and college students, on particular experimental methods and in using specialised laboratory tools. Help within the supervision of undergraduate and postgraduate college students

The IndividualData, Abilities and Expertise

• Expertise in undertaking administration and precedence setting
• Experience in up to date molecular biology methods
• Experience in recombinant protein expression in micro organism and in insect/mammalian cells for structural research
• Experience in protein purification and characterisation
• Presentation of labor at scientific conferences
• Experience with biochemical and biophysical methods for assessing protein high quality and/or protein-ligand interactions
• Experience with protein crystallisation
• Thorough working information of Well being and Security procedures
• Wonderful crew working expertise
• Demonstratable technical and problem-solving capability and a capability for authentic thought
• Good IT and computing expertise
• Willingness to be taught new methods and develop experimental ability set
• Capability to contribute to design and specification of analysis/instructing actions

Fascinating

• Good organising capacity to satisfy deadlines, with a constructive and proactive strategy to duties and diligence and a spotlight to element
• Capability to adapt to modifications in laboratory analysis priorities.

Attributes and Behaviour

• Tact, diplomacy and capable of deal with tough conditions
• Capability to satisfy deadlines with efficient time and useful resource administration
• Clear communicator and lively listener
• Constant and acceptable strategy to employees and conditions
• Use of suggestions for course of enchancment and employees improvement
• Workforce participant, self starter and capable of handle complicated workload
• Capability to reply enthusiastically and positively to undergraduate college students

{Qualifications}

• Bachelor’s diploma (or equal) in a related science topic – ideally biomedical/biochemistry
• Analysis expertise in protein expression in insect cells, protein biochemistry, biophysics or X-ray crystallography

Fascinating

• Masters qualification in a related topic

Newcastle College is a worldwide College the place everyone seems to be handled with dignity and respect. As a College of Sanctuary, we goal to supply a welcoming place of security for all, providing alternatives to folks fleeing violence and persecution.We’re dedicated to being a completely inclusive college which actively recruits, helps and retains colleagues from all sectors of society. We worth range in addition to rejoice, assist and thrive on the contributions of all of our workers and the communities they characterize. We’re proud to be an equal alternatives employer and encourage purposes from people who can complement our present groups, we consider that success is constructed on having groups whose backgrounds and experiences mirror the variety of our college and scholar inhabitants.At Newcastle College we maintain a silver award in recognition of our good employment practices for the development of gender equality. We additionally maintain a Bronze award in recognition of our work in direction of tackling race inequality in increased schooling REC. We’re a employer and can supply an interview to disabled candidates who meet the important standards for the function as a part of the supply and interview scheme.As well as, we’re a member of the Euraxess initiative supporting researchers in Europe.Requisition ID: 26859

Anticipated wage

Location

Newcastle

Job date

Fri, 22 Mar 2024 23:15:33 GMT

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