Research Fellow
University College London
About usWe are one of the world’s leading research centres for the study of prions and their wider relevance to neurodegenerative disease with a growing research activity in Alzheimer’s disease (www.prion.ucl.ac.uk).The Institute is highly multidisciplinary with close integration of structural and molecular biology, genetics, cellular and animal models, small molecule and immuno-therapeutics and clinical research.MRC and UCL have jointly invested £30 million in provision of a dedicated building in central London for the Institute supporting the vision to expand research in protein misfolding and aggregation in neurodegenerative disease.About the roleWe have an exciting opportunity for a Research Fellow to join our team.Following an initial training period you will undertake research to investigate the structures of infectious prion strains using atomic force microscopy (AFM). The existence of prion strains constitutes protein-based inheritance and the structural basis of this is of wide biological and evolutionary interest. In addition understanding how certain assemblies of misfolded proteins can act like pathogens spreading throughout the brain is a major research focus in neurodegeneration. AFM work will be conducted using dedicated microscopes at the Prion Unit.Ad hoc overnight visits to collaborating laboratories within the UK may be occasionally required.An acceptable DBS check is required to carry out this roleThis is a fixed-term role until 31st March 2028 in the first instance.Appointment at Grade 7 is dependent upon having been awarded a PhD; if this is not the case, initial appointment will be at Grade 6B.This role meets the eligibility requirements for a skilled worker certificate of sponsorship or a global talent visa under UK Visas and Immigration legislation. Therefore, UCL welcomes applications from international applicants who require a visa.’About youA background in AFM and protein structural biology is essential.Excellent verbal and written communication skills are required to communicate research findings in peer reviewed journals and scientific presentations.Experience of working in microbiological containment level 3 facilities would be an advantage.The post-holder will work closely with existing staff at UCL and Birkbeck College but must have the ability to work independently.Additional Information:
to find out more.What we offerAs well as the exciting opportunities this role presents, we also offer some great benefits some of which are below:
Visit to find out more.Our commitment to Equality, Diversity and InclusionAs London’s Global University, we know diversity fosters creativity and innovation, and we want our community to represent the diversity of the world’s talent. We are committed to equality of opportunity, to being fair and inclusive, and to being a place where we all belong.We therefore particularly encourage applications from candidates who are likely to be underrepresented in UCL’s workforce.These include people from Black, Asian and ethnic minority backgrounds; disabled people; LGBTQI+ people; and for our Grade 9 and 10 roles, women.Athena Swan Status StatementOur department holds an Athena SWAN Bronze award, in recognition of our commitment to advancing gender equality.Available documents
North West London
Wed, 12 Feb 2025 05:39:59 GMT
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