Scientist I, Biology

Job title:

Scientist I, Biology

Company

Insmed EU Careers

Job description

Company Description:Insmed is a global biopharmaceutical company on a mission to transform the lives of patients living with serious and rare diseases. Our most valuable resource is our employees, and everything we do is motivated by a patients-first mentality. We are dedicated to growing our team with talented individuals from around the world who are willing to challenge the status quo, solve problems, and work collaboratively with a sense of urgency and compassion.Guided by our core values of collaboration, accountability, passion, respect, and integrity, we aim to foster an inclusive, diverse, and flexible work environment, where our employees are recognized for leaning in and rolling up their sleeves. If you share our vision and want to work with the most dedicated people in the biopharma industry, come to Insmed to accelerate your career. Recognitions:Consistently Ranked Science’s Top EmployerInsmed is dedicated to creating a collaborative environment where our team can thrive. Every day, our employees turn their passion for science and research into innovative solutions for patients. That’s why we’ve been named the No. 1 company to work for in the biopharma industry in Science’s Top Employers survey for four years in a row.A Certified Great Place to Work®We believe our company is truly special, and our employees agree. In July 2024, we became Great Place to Work-certified in the U.S. for the fourth year in a row. We are also honored to have been listed on the Best Workplaces in Biopharma™, Best Workplaces in New York™, PEOPLE® Companies That Care, Best Workplaces for Women™, Best Workplaces for Millennials™, and Best Medium Workplaces™ lists.Summary: Insmed Cambridge are advancing an early-stage research engine encompassing a wide range of technologies and modalities to deliver powerful new ways of treating a broad range of serious and rare diseases. We are seeking a highly motivated and innovative Scientist to join our Target Discovery team. In this role, you will leverage your deep expertise in cell and molecular biology to develop complex disease-relevant cellular models and assays to enable validation of identified targets. You will be a key member in a dynamic research team collaborating closely with interdisciplinary research teams, including experts in functional genomics, drug discovery, bioinformatics, and various disease areas, to translate scientific discoveries into groundbreaking therapeutics. Responsibilities:

• Plan and execute mechanism of action studies to understand disease biology and target efficacy using genetic editing and chemical biology approaches as agreed upon with the project team.
• Design and implement molecular and phenotypic assays to characterise in vitro disease models and validate targets
• Independently solve technical problems encountered during experimental procedures.
• Evaluate results, draw conclusions and implement process improvements.
• Ensure that all studies are efficiently executed and aligned to agreed procedures.
• Maintain project schedules.
• Participate and present data in company discussions to facilitate project progression and meetings with external academic and commercial parties.
• Provide accurate documentation of work in the form of electronic lab notebook and reports.
• Maintain effective working relationships with other company employees.
• Stay up to date with scientific literature and maintain an awareness of current and emerging techniques/technologies.

Position Requirements:

• PhD Degree or equivalent experience in in cell biology/cellular assays (experience working in biotech environment advantageous).
• Experience with nucleic acid-based (such as DNA extractions, designing and optimising primers and probes for PCR, real-time PCR) and protein-based (such as WesternBlot, ELISA) technologies.
• Strong understanding and knowledge of mammalian cell biology, including cell engineering, flow cytometry and immunofluorescence microscopy.
• Experience working with advanced patient-derived cell models and/or culture and differentiation of iPSCs.
• Experience in design and implementation of cell and phenotypic assays to characterise in vitro disease models and validate targets
• Working knowledge of verification and validation processes, including optimisation and troubleshooting assays.
• Competence in high content imaging, including analysis, would be advantageous.
• Self-starter with strong planning and problem-solving skills.
• Excellent communication, team collaboration and presentation skills.
• Able to work effectively in a matrix environment and deliver in accordance to agreed timelines.
• Strong scientific background and demonstrated record of achievements through scientific publications
• Occasional weekend work is required.

Compensation & Benefits:At Insmed, we’re committed to investing in every team member’s total well-being, now and in the future. Our benefit programs vary by country but we offer the following to all Insmed team members, regardless of geographic location:

• Flexible approach to how we work
• Health benefits and time-off plans
• Competitive compensation package, including bonus
• Equity Awards (Long-Term Incentives)
• Employee Stock Purchase Plan (ESPP)

For more information on U.S. benefits .Additional Information:Insmed Incorporated is an Equal Opportunity/Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law.Unsolicited resumes from agencies should not be forwarded to Insmed. Insmed will not be responsible for any fees arising from the use of resumes through this source. Insmed will only pay a fee to agencies if a formal agreement between Insmed and the agency has been established. The Human Resources department is responsible for all recruitment activities; please contact us directly to be considered for a formal agreement.Insmed is committed to providing access, equal opportunity, and reasonable accommodation for individuals with disabilities in employment, its services, programs, and activities. To request reasonable accommodation to participate in the job application or interview process, please contact us by email at and let us know the nature of your request and your contact information. Requests for accommodation will be considered on a case-by-case basis. Please note that only inquiries concerning a request for reasonable accommodation will be responded to from this email address.Applications are accepted for 5 calendar days from the date posted or until the position is filled.

Expected salary

Location

Cambridge

Job date

Wed, 26 Mar 2025 04:51:35 GMT

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