Senior Research Associate in Medicinal Chemistry/Chemical Biology

Job title:

Senior Analysis Affiliate in Medicinal Chemistry/Chemical Biology

Firm

College of East Anglia

Job description

An thrilling alternative has arisen for a Senior Analysis Affiliate be a part of the Faculty of Pharmacy to conduct research on the management of protein-protein interactions in ribosome biogenesis.A characteristic of most cancers is a capability to develop quickly, repeatedly, and uncontrollably. Most cancers generally achieves this by creating additional ribosome complexes, permitting for uncontrollable protein synthesis and most cancers cell progress. Lots of the medicine that we already use to deal with most cancers have an effect on ribosome biogenesis, nevertheless, the medicine should not particular giving us unintended effects. On this analysis we are going to make a compound that may have an effect on ribosome biogenesis selectively, giving us a extremely efficient drug with far lowered unintended effects and a broad-spectrum most cancers remedy. This challenge will use a brand new method, developed in our analysis group, to make molecules that management the protein-protein interactions in ribosome biogenesis. Utilizing peptides as scaffolds, sections will be changed with drug items to make a drug molecule. Work will give attention to designing molecules for this goal and creating them to be good precision medication leads.As a Senior Analysis Affiliate you may be related to this EPSRC funded challenge and can contribute concepts and/or enhancement of strategies or methodologies. You’ll analyse and interpret information, write up outcomes and current info on analysis progress and outcomes. Additionally, you will have the chance to contribute to grant functions and could also be concerned within the supervision of researchers and educating of scholars throughout the Faculty.You’ll have a PhD in Chemistry, Pharmaceutical Sciences, Biochemistry or a related analysis space. You’ll have sensible abilities able to resulting in impartial, unique contributions to the topic space. You’ll have sturdy interpersonal and communication abilities, with the flexibility to make use of initiative and apply creativity to resolve issues and the flexibility to speak advanced info clearly. Superior abilities immediately regarding protein and peptide synthesis, natural synthesis, or biophysical assays can be advantageous.This full-time submit is out there from 1st October 2024 on a set time period foundation for 14 months.We strongly encourage candidates from Black, Asian or different minority ethnic backgrounds and welcome functions from all protected teams as outlined by the Equality Act 2010. Appointment can be made on benefit.Additional info on our nice advantages bundle, together with 44 days annual depart inclusive of Financial institution Holidays and extra College Customary days, will be discovered on our web page.The College holds an Athena Swan Silver Institutional Award in recognition of our development in direction of gender equality.Beginning wage from £37,099 each year, depending on abilities and expertise, with an annual increment as much as £44,263 each year

Anticipated wage

£37099 per 12 months

Location

Norwich

Job date

Fri, 29 Mar 2024 08:15:12 GMT

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