Structural Mass Spectrometry Scientist

University of Leeds


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As a structural mass spectrometry scientist, you’ll help the vary of mass spectrometry modalities which might be out there within the facility, together with hydrogen-deuterium trade, native MS, intact protein mass measurement, proteomics and metabolomics. You’ll present an environment friendly analytical service for customers of the Facility, performing analyses for customers, give recommendation to others concerning pattern preparation, experimental design and information interpretation, actively set up inside and exterior hyperlinks with different analysis teams and industrial companions, develop new methods for biomolecular evaluation, write technical summaries and undertaking studies, keep the mass spectrometry and chromatography tools in good working order, and carry out different common laboratory duties.

As a Structural Mass Spectrometry Scientist your fundamental duties will embrace:

  • Main the design and execution of analysis packages utilizing the Facility’s hydrogen-deuterium exchange-MS, native-MS, proteomics and metabolomics [FS1] platforms;
  • Designing experimental and information evaluation workflows to be utilized to cutting-edge analysis programmes utilizing superior mass spectrometry methods;
  • Develop new methods for biomolecular evaluation, in collaboration with tutorial workers and facility customers, e.g. pattern preparation, purification and evaluation, together with chromatographic methodology and ion mobility, and by growing hybrid options combining totally different MS approaches;
  • Utilizing your in-depth understanding of the structural MS toolbox of approaches out there for optimising pattern preparation and strategies to acquire information of the best high quality; 
  • Working in shut collaboration with the tutorial leads of the Facility, Prof. Frank Sobott and Dr Anton Calabrese, and colleagues from the College of Leeds and exterior industrial customers, having accountability for his or her consumer expertise; 
  • Growing information processing pipelines to help the analysis neighborhood, together with liaising with IT; 
  • Taking the lead speaking analysis outcomes utilizing written studies, information/figures for publications or grant functions, shows and conducting common progress conferences with exterior/inside prospects; 
  • Improvement, manufacturing and supply of coaching packages and materials for researchers in any respect expertise ranges; 
  • Taking part in a precept function in upkeep and troubleshooting of extremely specialist tools, working carefully with area service engineers to maximise instrument operation time; 
  • Contributing to a world-class, collaborative analysis surroundings, together with mentoring junior researchers, and sustaining your individual persevering with skilled improvement, significantly retaining up-to-date with know-how related to structural mass spectrometry. 

These duties present a framework for the function and shouldn’t be thought to be a definitive record. Different affordable duties could also be required in line with the grade of the put up.

To discover the put up additional or for any queries you might have, please contact:

Prof. Frank Sobott , Chair in Biomolecular Mass Spectrometry

Electronic mail: [email protected]

Dr. Anton Calabrese , Sir Henry Dale Fellow & College Tutorial Fellow

Electronic mail: [email protected]  

Location:  Leeds – Most important Campus
School/Service:  School of Organic Sciences
College/Institute:  Organic Sciences School Workplaces
Class:  Technical Help
Grade: 
Grade 7
Wage: 
£37,099 to £44,263
every year
Working Time:  100%
Submit Sort: 
Full Time
Contract Sort:  Ongoing
Launch Date:  Friday 15 March 2024
Closing Date:  Friday 12 April 2024
Interview Date: 
To be confirmed
Reference:  FBSFO1203
Downloads:  Candidate Transient

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